Prevalence of Opportunistic Intestinal Parasitic Infections and Associated Risk Factors Among Hiv Sero-Positive Indviduals at Hiwot Fana Specialized University Hospital, Harar Town,Eastern Ethopia

Prevalence of Opportunistic Intestinal Parasitic Infections and Associated Risk Factors Among Hiv Sero-Positive Indviduals at Hiwot Fana Specialized University Hospital, Harar Town,Eastern Ethopia

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Title: Prevalence of Opportunistic Intestinal Parasitic Infections and Associated Risk Factors Among Hiv Sero-Positive Indviduals at Hiwot Fana Specialized University Hospital, Harar Town,Eastern Ethopia
Author: Merid, Tadesse; Dr. Sissay, Menkir
Abstract: Opportunistic intestinal parasite infections (OIPIs) are the major public health problems among Human immune virus/Acquired immunodeficiency syndrome (HIV/AIDS) patients and other immunocompromised individuals in most developing countries including Ethiopia. This study was aimed at determining the prevalence of OIPIs and associated risk factors among HIV seropositive individuals at Hiwot Fana Specialized University Hospital (HFSUH), Harar Town, Eastern Ethiopia. A cross-sectional study was carried out at HFSUH, from March-May, 2014. In addition, a retrospective analysis of clinical records was also carried out. Using serial a sampling method, a total of 422 HIV sero-positive individuals were included both from out patient and in patient departments. Stool samples were collected and processed by using the direct wet mount, formol-ether concentration method and modified Ziehl Neelsen methods. Blood samples were collected to determine the CD4+ T cell count and the status of the study participants. Structured and pre-tested questionnaire was used to gather relevant information on socio-demographic and risk factor data. Data were analyzed using SPSS statistical software version 16.0. Chi-square, Odds ratio and p-value were used to verify a possible association between OIPI and the risk factors. The overall prevalence of OIPI in the study area was 40.3%. Major OIP species identified were Cryptosporidium species 5.2%, Isospora belli 4.3%, Cyclospora cayatenensis 2.1%, Blastocystis hominis 0.96% and Strongyloides stercolaris 4.3%. Giardia lamblia 8.1%, and Entamoeba histolytica/dispar 10.7% were the non-opportunistic intestinal parasites Prevalence of OIP was significant in diarrheal stools and among patients with lower CD4+ (<200 cell/mm3) with prevalence of 67.6% and 60.5%, respectively. Significant relation between OIPIs and risk factors like chewing Khat, eating unwashed and raw vegetables, contact with animal, absence of latrine facility, poor sanitation practice, low level educational status and poor biomedical knowledge (P<0.05). Continuous guidance and counseling should be given from Hospitals and health centers for HIV/AIDS patients to minimize the risk of being infected by OIPs.
Description: 100p.
URI: http://hdl.handle.net/123456789/3256
Date: 2014-10


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