Prevalence of Opportunistic Intestinal Parasitic Infection Among Hiv/Aids Patients Attending Othona Hospital ,Wolayita Sodo,Southern Ethiopia

Prevalence of Opportunistic Intestinal Parasitic Infection Among Hiv/Aids Patients Attending Othona Hospital ,Wolayita Sodo,Southern Ethiopia

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Title: Prevalence of Opportunistic Intestinal Parasitic Infection Among Hiv/Aids Patients Attending Othona Hospital ,Wolayita Sodo,Southern Ethiopia
Author: Menbereleul, Mathewos; Dr. Sissay, Menkir
Abstract: It was well known that opportunistic intestinal parasitic infections among HIV/AIDS patients were high in developing countries compared with industrialized countries. Because of unhygienic conditions transmission of these parasites was more frequent in developing countries. The objective of this study was to determine the prevalence of opportunistic intestinal parasitic infections among HIV/AIDS patients with special emphasis on Cryptosporidium parvum, Isospora belli, Cyclospora cayetanensis and Blastocystis hominis infections as well as their associations with some socio-demographic risk factors and CD4+ T cell counts at different immunity levels. A hospital based cross sectional study and the five years retrospective analysis of clinical records was carried out from May-August, 2013 in Othona Hospital, Wolayita Sodo, Southern Ethiopia. Using serial sampling method, a total of 422 HIV/AIDS patients aged from 5- 65 years old were included in this study. The samples were collected from all people living with HIV/AIDS until the sample size was reached. A pre-tested and structured questionnaire was employed to collect socio-demographic data and health record analysis of the patients. Stool samples were collected from 422 HIV/AIDS patients and were processed for opportunistic intestinal parasites using Modified Ziehl-Neelsen staining method, formol-ether concentration and by direct wet mount methods. Data was analyzed using the SPSS version-16. Chi-square and logistic regression were used to verify possible strength of opportunistic intestinal parasitic infection and exposure with different risk factors. Simultaneously, CD4+Tcell counts were recorded to assess the status of HIV/AIDS infection in relation to opportunistic parasitic infections. Out of 422 HIV/AIDS patients, opportunistic intestinal parasites were recorded from 268(63.5%) patients. Among these, C.parvum (14.2%), I. belli (8.5%), C.cayetanensis (2.8%) and B.hominis (2.6%) was predominant coccidian protozoan parasite identified from HIV/AIDS patients. In addition to opportunistic intestinal parasites, non-opportunistic intestinal protozoan parasites such as, Giardia lamblia (10.0%) and Entamoeba histolytica (9.0%) were also prevalent in HIV/AIDS patients. Among helminths, Strongloides stercolaris (10.2%) was the predominant helminthic parasite isolated in HIV/AIDS patients followed by Ascaris lumbricoides (2.0%) and Hooke worm (1.2%) among the study participants. In general, this study shows that the high prevalence of opportunistic intestinal parasitic infections among HIV/AIDS patients and its association with the lower CD4+ T cell counts (<200cells/μl). Therefore, regular monitoring of CD4+T cell counts and screening of these opportunistic agents in the HIV/AIDS patients will help to reduce the mortality and morbidity with administration of appropriate therapy.
Description: 91p.
URI: http://hdl.handle.net/123456789/3255
Date: 2014-01


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